Open to the public since the middle of the 18th century—and subsequently expanded by various Saxon Electors and museum curators—this celebrated museum contains one of Germany’s finest collections of Old Master works. Housed in the magnificent Dresden Zwinger, the museum spans three floors, focusing mainly on European painting (specifically the Italian Renaissance) but also featuring Dutch and Flemish masters like Van Eyck, Dürer, Holbein, Rubens, and Rembrandt. Highlights include Raphael’s Sistine Madonna, Vermeer’s Girl Reading a Letter at an Open Window, and Bellotto’s depictions of Dresden’s historic city center. Also worth checking out is the collection of Cranach paintings—the largest of its kind in the world.